Abstract: This article is about the drug treatment of hyperphosphataemia.Division Villam hydrochloride is a cationic polyme ,Major components hydrochloride polyacrylamide, can be combined with the phosphorus.Physiological pH, the protonated amino almost entirely through the combination of ion exchange of phosphorus in the gastrointestinal tract hydration expansion into several times the original volume of the gel, And not by intestinal absorption. Clinical trials show that the Secretary Villam hydrochloride can effectively reduce serum phosphorus levels, the effect can be comparable with the phosphate binder. Secretary Villam hydrochloride does not cause hypercalcemia, can significantly reduce the incidence of cardiovascular disease. In addition, the application of hydrochloric acid Division Villam reduce phosphorus, you can control the use of calcitriol secondary hyperparathyroidism. Currently the Division Villam hydrochloride is considered an ideal phosphate binder. But it was reported slightly lower hydrochloride Division Villam blood bicarbonate levels, reduce the fat-soluble vitamins A, D, E, K absorption and other side effects, its clinical application is limited. Long-term use hydrochloride Division Villam security is yet to be verified.
