Abstract
Porphyrins is the porphine outer ring has the substituent group homolog and the derivative general terms, when in after its nitrogen two protons by metallation, namely becomes metalloporphyrins. Porphyrin plays an important role in the field of life science. Many biological phenomena are depend on porphyrins and its complexes. In recent years, synthesis and application of porphyrin has been payed increasing attention to.
All over the world, mang scientists on their research it is very deeper and active. In our life process, if we could understand these compounds’ function, we will develop and use them better. Therefore, studies on the synthesis,structure and properties of porphyrin and metalloporphyrins have been regarded seriously.
Based on single factor experiment method is used to explore the method and the reactive conditions of synthesis for a metalloporphyrin—tetra(m-chlorphenyl)- porphyrin manganese(TCPPMn). The experimental results show that: (1) The TCPPMn has been synthesized from 3-chlorbenzaldehyde, pyrrole and acetate manganese by two-step method. First, the tetra(3-chlorphenyl)porphyrin(TCPP) is synthesized from 3-chlorbenzaldehyde and pyrrole, then the TCPPMn is synthesized from TCPP and acetate manganese. (2) The reaction condition of synthesis for TCPP is as follows: the reactive solvent is propionic acid, the molar ratio of pyrrole and 3-chlorbenzaldehyde is 1.00:1.02, the concentration of pyrrole is 0.32mol.L-1, the reactive time is 45 min, the reactive temperature is the temperature of solvent refluxing. In the condition, the yield of TCPP is more than 18%. (3) The reaction conditions of synthesis for TCPPMn is as follows: the reaction solvent is DMF, the molar ratio of TCPP and acetate manganese is 1:8, the concentration of TCPP is 0.0222mol.L-1; the reactive time is 4h, the reactive temperature is the temperature of solvent refluxing. Under the conditions, the yield of TCPPMn is more than 85%.
