Abtract This topic is human pulse measuring instrument design. As the particularity of the pulse signal, care must be taken in the design to achieve accurate measurements. The focus of the system lies in the simplicity of measurements required to achieve and precise. System should be less than ten seconds, the measured one minute pulse of the human body, and more than two times to ensure error. This system 89S51 microcontroller as the center of the system by using a single chip to achieve the pulse of the core computing functions. Front-end processing of the signal, the use of piezoelectric ceramic body acquisition pulse signal is then amplified through the AD620, Schmitt trigger shaping, low-pass filter and a series of operation, the pulse signal is converted to a pulse signal with the input frequency to the microcontroller, the microcontroller and use them count. Employing a transmissive detection methods to determine human blood oxygen saturation is already more mature guardianship means, in the clinical and home care settings with a wide range of applications, but many need to be reflected in the detection of the occasion, such as brain oxygen, muscle oxygen , fetal oxygen and other clinical care, how to use non-invasive, economical method to obtain accurate and reliable oxygen saturation values remain constantly in the field of biomedical engineering to explore the issue. Keywords: oxygen saturation transmissive reflective
