SVHC檢測—鄰苯二甲酸酯類物質

制藥工程論文編號:ZY036    論文字數:11078,頁數:28

目  錄
中文摘要 I
英文摘要 II
目錄 III
1. 緒論 1
 1.1 研究的背景 1
 1.2 研究的意義 3
 1.3 鄰苯二甲酸酯簡介 4
 1.4 本章小結 8
2. 實驗部分 9
 2.1 GC-MS技術實驗原理 9
 2.2 實驗試劑和材料 10
 2.3 實驗儀器和設備 10
 2.4 實驗步驟 10
3. 結果與討論 12
 3.1 氣相色譜-質譜定性結果分析 12
 3.2 氣相色譜-質譜定量結果分析 14
 3.3 儀器精確度分析 16
 3.4 塑料樣品中SVHC物質DEHP含量分析 17
 3.5 REACH法規下，含有SVHC的物品的義務 18
 3.6 小結 18
4．總結與展望 19
 4.1 總結 19
 4.2 展望 19
致謝 21
參考文獻 22

摘 要：歐盟《關于化學品注冊，評估，授權與限制》（簡稱REACH法規）是歐盟對進入其市場的所有化學品進行預防性管理的一部法規。“高關注物質”簡稱SVHC，是法規中的一個特有名詞，頻繁出現在檢測，授權，限制等內容中。 鄰苯二甲酸酯(PAEs)廣泛以增塑劑等形式存在于化學行業，與人類的生活棲息相關。同時，PAEs也被視為環境常見的污染物之一，是世界衛生組織(WHO)1995年公布的必須控制的一類擾亂內分泌的化學物質。因其隨著時間的推移可從基質中釋放遷移出來，且在環境中穩定持久，具有生物累積和放大效應，最終通過食物鏈而危及人類健康。本文用氣相色譜-質譜聯用技術(GC-MS)對已被列入15項高關注物質清單的鄰苯二甲酸酯類（鄰苯二甲酸二丁基酯(DBP)，鄰苯二甲酸二（2-乙基己基）酯(DEHP)，鄰苯二甲酸甲苯基丁酯(BBP)在塑料及其相關產品進行分析研究。

關鍵詞：REACH法規；高關注物質；鄰苯二甲酸酯；氣相色譜-質譜聯用技術

Abstract: The EU REACH regulation is the EU's access to their markets for all chemicals of a preventive management regulation. "Substances of Very High Concern" referred to SVHC, is one of specific term to the the regulations, which frequently appears in the detection, authorization, and restrictions. Phthalic acid esters (PAEs) as a kind of plasticizer are widely used in the chemical industry, and have a deep relation with human's life. At the same time, the PAEs are also considerated as a common pollutant to the environment. The World Health Organization (WHO) announced that it was necessary to control the use of this kind of endocrine disrupting chemicals in 1995. As the time passby, it can release from the matrix, migration out, last stability in the environment, causing bio-accumulation and amplification. Ultimately, endanger human health through the food chain. In this paper, the technology used in detection of benzyl butyl phthalate (DBP), bis(2-ethylhexyl) phthalate(DEHP), dibutyl phthalate(BBP)) in the list of SVHC is the gas chromatography - mass spectrometry (GC-MS).

Keywords: REACH regulations; Substances of very high concern; Phthalic acid esters; Gas chromatography - mass spectrometry