紫外可見光譜法研究甘氨酸與亞鐵離子配位現象

制藥工程論文編號:ZY049    論文字數:11825,頁數:30

目  錄
中文摘要………………………………………………………………………………I
英文摘要………………………………………………………………………………II
目錄……………………………………………………………………………………III
1. 緒論…………………………………………………………………………………1
 1.1甘氨酸螯合物的概述……………………………………………………………1
 1.2甘氨酸亞鐵的合成………………………………………………………………2
1.3 甘氨酸亞鐵的研究進展…………………………………………………………5
2 實驗部分………………………………………………………………………………8
 2.1 試劑與儀器………………………………………………………………………8
 2.2 實驗方法…………………………………………………………………………8 
 
3  結果與結論………………………………………………………………………10
 3.1配合物的吸收光譜……………………………………………………………10
 3.2 配合物的組成…………………………………………………………………11
 3.3甘氨酸與亞鐵離子配位反應的級數…………………………………………13
 3.4 溫度對甘氨酸與亞鐵離子配位反應的影響…………………………………15
 3.5 離子強度對甘氨酸與亞鐵離子配位反應的影響……………………………17
 3.6 溶劑PH對甘氨酸與亞鐵離子配位反應的影響………………………………19
 3.7 討論……………………………………………………………………………21
4．總結與展望…………………………………………………………………………22
致謝……………………………………………………………………………………24
參考文獻………………………………………………………………………………25

摘 要：本論文用紫外-可見光譜法研究甘氨酸與亞鐵離子的配位反應。考察了溫度、離子強度、配位比及pH值等對配位反應的影響。結果表明：當離子強度為I=0.02；甘氨酸與亞鐵離子配位比（Gly／Fe）為4：1；pH=5.0時，反應的速率常數最大，而溫度對配位反應的影響表現不是很突出。甘氨酸與亞鐵離子的配位反應為二級反應，反應活化能為4.488KJ/mol，自由能△G≠為2.012KJ/mol。同時本文提出了甘氨酸與亞鐵離子配位反應的合理機理，為高純甘氨酸亞鐵的制備提供理論依據。

關鍵詞：甘氨酸亞鐵；紫外可見光譜法；配位反應；動力學

Abstract:In this paper, the complexation between glycine and ferrous ions was studied by UV - Vis spectroscopy .The influences of complexation, such as temperature, ionic strength, coordination and pH value were observed. The result shows that: the ionic strength I = 0.02;the complex rate of glycine and ferrous ions (Gly / Fe) is 4:1; pH = 5; formation rate of the complexation was the largest separately, and the temperature will not affect the the formation rate obviously. The complexation between glycine and ferrous ions was second-order reaction, Activation energy was 4.488KJ/mol ,and free energy △G≠ was 2.012KJ/mol. The possible reaction mechanism for the complexation between glycine and Fe(Ⅱ) was proposed. The theoretical basis was provided for the preparation of high purity ferrous glycine.

Key words：ferrous glycine；   UV-Vis spectroscopy ；  complexation ;  dynamaics